The A55 has been closed in both directions near the Posthouse roundabout after a crash which has left a lorry on its side.
Cheshire Fire and Rescue Service says emergency services have been deployed to the incident near Caldy Valley, by Junction 39 (Sainsbury's Roundabout).
Traffic is building up in both directions, with congestion on the eastbound carriageway as far back as the Posthouse Roundabout (Junction 38) and westbound tailbacks as far back as the M56 interchange on the M53 motorway (junction 11).
North West Motorway Police report an HGV is on its side between the Tarvin Roundabout A51 down to the slip road with the A41.
Motorists are being advised to expect delays and seek alternative routes if possible.
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